RAF Typhoon FGR4s have joined forces with France's air force in a combined operation targeting an underground arms cache in Syrian territory operated by the Daesh militant organization, according to the UK Ministry of Defence.
The facility, pinpointed through surveillance, was believed to be housing weapons and explosive materials, the announcement noted, and was positioned in hills just above Palmyra in Syria's central region.
"The RAF jets utilized Paveway IV guided bombs to hit a number of approach shafts providing entry to the site... early reports suggest the objective was successfully hit," the MoD said.
There was no indication of any harm to civilians in the operation on Saturday evening and every plane involved returned safely, the defence officials confirmed.
The British jets were supported by a Voyager aerial refuelling aircraft.
IS - also known as the so-called Islamic State - enforced extremist governance over parts of Syria and Iraq until 2019.
"This operation demonstrates British leadership, and determination to work closely with our partners, to eradicate any revival of Daesh and their harmful and extremist ideologies in the area," UK Defence Secretary the Defence Secretary said.
British military aircraft have performed overwatch operations over Syrian airspace to "forestall any efforts to regroup" of the group after its defeat at the battle of Baghuz in 2019, the authorities noted.
"I must thank the personnel of our armed forces involved in this strike for their expertise and their courage," Healey said. "They were among a great many UK service members on duty over Christmas and New Year. This action, to eliminate militants who threaten our way of life, highlights how our armed forces are always on standby, throughout the year, protecting the UK domestically and strong abroad."
During December, the US military executed what it termed a "massive strike" targeting Islamic State objectives in Syria, following an assault claimed the lives of two US servicemembers and a civilian linguist in Palmyra.
The UN says Daesh still has between 5,000 and 7,000 fighters in Syria and Iraq.